- Title
- Long-term improvements after multimodal rehabilitation in late phase after stroke: a randomized controlled trial
- Creator
- Bunketorp-Käll, Lina; Lundgren-Nilsson, Åsa; Samuelsson, Has; Pekny, Tulen; Blomvé, Karin; Pekna, Marcela; Pekny, Milos; Blomstrand, Christian; Nilsson, Michael
- Relation
- Stroke Vol. 48, Issue 7, p. 1916-1924
- Publisher Link
- http://dx.doi.org/10.1161/STROKEAHA.116.016433
- Publisher
- Lippincott Williams & Wilkins
- Resource Type
- journal article
- Date
- 2017
- Description
- Background and Purpose: Treatments that improve function in late phase after stroke are urgently needed. We assessed whether multimodal interventions based on rhythm-and-music therapy or horse-riding therapy could lead to increased perceived recovery and functional improvement in a mixed population of individuals in late phase after stroke. Methods: Participants were assigned to rhythm-and-music therapy, horse-riding therapy, or control using concealed randomization, stratified with respect to sex and stroke laterality. Therapy was given twice a week for 12 weeks. The primary outcome was change in participants' perception of stroke recovery as assessed by the Stroke Impact Scale with an intention-to-treat analysis. Secondary objective outcome measures were changes in balance, gait, grip strength, and cognition. Blinded assessments were performed at baseline, post-intervention, and at 3- and 6-month follow-up. Results: - One hundred twenty-three participants were assigned to rhythm-and-music therapy (n=41), horse-riding therapy (n=41), or control (n=41). Post-intervention, the perception of stroke recovery (mean change from baseline on a scale ranging from 1 to 100) was higher among rhythm-and-music therapy (5.2 [95% confidence interval, 0.79-9.61]) and horse-riding therapy participants (9.8 [95% confidence interval, 6.00-13.66] ), compared with controls (-0.5 [-3.20 to 2.28]); P=0.001 (1-way ANOVA). The improvements were sustained in both intervention groups 6 months later, and corresponding gains were observed for the secondary outcomes. Conclusions: Multimodal interventions can improve long-term perception of recovery, as well as balance, gait, grip strength, and working memory in a mixed population of individuals in late phase after stroke. Clinical Trial Registration - URL: http//www.ClinicalTrials.gov. Unique identifier: NCT01372059.
- Subject
- cognition; follow-up studies; music; randomized controlled trial; rehabilitation; stroke
- Identifier
- http://hdl.handle.net/1959.13/1393644
- Identifier
- uon:33578
- Identifier
- ISSN:0039-2499
- Rights
- This is a non-final version of an article published in final form in Stroke available from http://dx.doi.org/10.1161/STROKEAHA.116.016433.
- Language
- eng
- Full Text
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